Childress Institute Awards Pediatric Trauma Device Grant

410 Medical Will Develop Rapid Blood Delivery System to Help Save Injured Children

 

WINSTON-SALEM, N.C. (November 15, 2016) – The Childress Institute for Pediatric Trauma announced the winner of its pediatric trauma medical device project. 410 Medical, founded by Dr. Mark Piehl, will receive $50,000 for the development of a rapid blood delivery system to help injured children.

 

“We are thrilled that Dr. Piehl and 410 Medical are producing a pediatric device to help emergency medical professionals save injured kids,” said Bob Gfeller, executive director of the Childress Institute for Pediatric Trauma. “This was our first foray into developing devices specifically for seriously injured children and we plan to continue the process with our next request for proposal with the Philadelphia Pediatric Medical Device Consortium.”

 

Dr. Piehl and his team created the LifeFlow®, a simple hand-operated rapid infusion device, to treat critically ill children needing rapid fluid delivery for conditions such as sepsis and trauma.  During development, Dr. Piehl determined that the LifeFlow could also be effective for delivering blood to patients in hemorrhagic shock.

 

The LifeFlow recently received FDA clearance for rapid fluid delivery of crystalloids and colloids, and will soon be in use at hospitals and EMS agencies. Research shows that early and aggressive fluid resuscitation saves lives in sepsis,1,2 yet fluid resuscitation guidelines are rarely achieved due to the complexity of vascular access and current fluid delivery methods. LifeFlow helps overcome these barriers, and allows front-line medical providers to quickly and efficiently provide fluids to critically ill patients.

 

The next generation LifeFlow device will enable rapid resuscitation with blood and blood products in a more efficient and effective manner than current techniques allow.  Since rapid administration of blood and blood products is essential therapy for severe trauma, LifeFlow could improve resuscitation and play an important role in the Golden Hour of trauma care for seriously injured children.

 

Traumatic injury is the leading killer of children in the U.S. over one year of age, and a leading killer of children worldwide.3,4 In 2014, over 10,000 children in America died of traumatic injury, with hemorrhage as one of the most important contributors to death.5 For every death there are 25 hospitalizations and almost 1,000 emergency room visits in the U.S. annually.6 Since a significant proportion of those hospitalized also suffer from hemorrhagic shock, over 100,000 children annually could benefit from improved resuscitation techniques.

 

The Childress Institute funds research, education and advocacy to save injured kids. In January 2016, the Childress Institute partnered with the Philadelphia Pediatric Medical Device Consortium (PPDC) to develop medical devices that address pediatric trauma, specifically the Golden Hour of care.

 

Since their first device development was successful, the Childress Institute and the PPDC launched their second joint project to fund the development and commercialization of a pediatric medical device to addresses the Golden Hour of pediatric trauma care. The first round of finalists will be selected December 9. For more information, visit www.PhillyPediatricMedDevice.org.

 

For more information about the Childress Institute and pediatric trauma, visit https://saveinjuredkids.org, https://www.facebook.com/SaveInjuredKids/ or Twitter @injuredkids.

 

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About the Childress Institute for Pediatric Trauma

Life threatening injury is the No. 1 killer of kids in America. Nearly 10,000 children lose their lives every year from serious injuries, and many more are treated in the emergency room. It can happen anywhere, at any time, to any child. The Childress Institute for Pediatric Trauma discovers and shares the best ways to prevent and treat severe injuries in children. The Institute funds research, education and advocacy to help improve the care and treatment injured kids receive across the U.S. The Childress Institute was founded at Wake Forest Baptist Medical Center in 2008 through a generous gift from Richard and Judy Childress. Visit www.SaveInjuredKids.org to learn more.

 

About the Philadelphia Pediatric Medical Device Consortium (PPDC)

The Philadelphia Pediatric Medical Device Consortium, or PPDC, aims to assist pediatric medical device innovators along the pathway from concept to commercialization. We provide innovators with the assistance and support needed to commercialize their technologies to improve pediatric medicine. Discover hospital pharmacy solutions by https://www.proxsysrx.com/. We understand that commercializing pediatric medical devices provides some unique challenges that are oftentimes not seen in the commercialization of medical devices for adults. We also understand that pediatric patients are not just small adults, and they need medical devices to fit their distinct needs. With funding from the U.S. Food and Drug Administration, we have developed the PPDC to bring pediatric medical device innovators over the common hurdles of commercialization. We do this through our advising support program, or Consortium Service Proposals, and through our competitive funding process, or Sponsored Project Proposals, which provides seed funding to a few promising projects per funding cycle. To learn more about the services we can offer, please select a button above that is most applicable to your organization. If you are interested in speaking with us, please see our brief Contact Us form.

 

About 410 Medical

410 Medical is a medical device company dedicated to developing innovative products that enable clinicians to improve care for critically ill patients. 410 Medical’s first product, LifeFlow®, is designed to enhance the speed and efficiency of fluid resuscitation, improving care for patients with life-threatening illnesses such as sepsis.  LifeFlow was cleared by the FDA for human use in August 2016. For more information, visit www.410medical.com .

 

Contact: 

Childress Institute:  Kara Thompson – kathomps@wakehealth.edu, (336) 491-9766

410 Medical: Kyle Chenet – kchenet@410medical.com, (919) 241-7900

 

Literature Cited

 

  1. Brierley J et al. Clinical practice parameters for hemodynamic support of pediatric and neonatal septic shock. Crit Care Med 2009; 37:666-88.
  2. Kissoon N et al. Updated American College of Critical Care Medicine – Pediatric Advanced Life Support Guidelines for Management of Pediatric and Neonatal Septic Shock. Pediatr Emer Care. 2010; 26: 867-869.
  3. Peden M,Oyegbite K,Ozanne-Smith J, et al, eds. World Report on Child Injury Prevention. Geneva, Switzerland: World Health Organization; 2008.
  4. Vital signs: Unintentional injury deaths among persons aged 0-19 years – United States, 2000-2009. Centers for Disease Control and Prevention (CDC) MMWR Morb Mortal Wkly Rep. 2012;61:270.
  5. Cocchi MN, Kimlin E, Walsh M, Donnino MW. Identification and resuscitation of the trauma patient in shock. Emerg Med Clin North Am. 2007 Aug. 25(3):623-42, vii.
  6. Daley BJ, et al. Considerations in Pediatric Trauma. http://emedicine.medscape.com/article/435031-overview#a2